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簡(jiǎn)要描述：Dihydropyrimidine dehydrogenase (DPYD) catalyzes the first rate-limiting step of the NADPH-dependent catabolism of uracil and thymine to dihydrouracil and dihydrothymine; thus, a deficiency of DPYD leads to an accumulation of uracil and thymine. Abnormal concentrations of these metabolites in bodily fluids may be the cause of neurological disease and a contraindication for treatment of cancer patients with certain pyrimidine analogs. DPYD also catalyzes the anticancer agent 5-fluorouracil (
產(chǎn)品型號(hào)：bsm-62352R廠商性質(zhì)：生產(chǎn)廠家更新時(shí)間：2025-03-03訪 問 量： 136產(chǎn)品分類
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